Diabetes pancreas, liver & muscle cells


Organ defect causes diabetes
Diabetes pancreas, liver & muscle cells
Glucose metabolism involve small intestine, pancreas, liver and muscle cell. If there are any problem with any of this diabetes organ leads to defect in glucose metabolism and can develop diabetes.
Functions of Insulin hormone
Insulin is a hormone, which controls and comments (signals) the whole glucose metabolism process. When food is digested, glucose (first nutrient released from food, which energies the whole body) is released in the blood stream. On seeing the high level of glucose in blood, pancreas releases certain quantity of insulin with respect to the level of glucose in blood to normalize the blood glucose level.
Insulin as a commenting signal
  • To muscle cells that informs there is enough glucose available for consumption
  • It is the commenting signal to liver to stop converting glycogen to glucose and releasing of glucose in the blood stream.
  • If there is high level of glucose in blood than the normal requirement then pancreas too releases high level of insulin with respect to the level of glucose. This high level of insulin is the blood is the commenting signal to liver to convert available excess glucose in blood to glycogen and store it for future requirements.
Diabetes pancreas
Diabetes may be caused if the pancreas that doesn’t make enough insulin to control the blood glucose level.
Diabetes and liver
Diabetes may be caused if the liver that releases glucose inappropriately, even when there is enough glucose in blood (& insulin in blood).
Diabetes Muscle cells
Diabetes may be caused if muscle cells that does not consume glucose, even if there is enough glucose and insulin in the blood called as insulin resistance.
Understanding diabetes organs defect that causes Type 2 diabetes
  • Type 2 diabetes may be caused if the pancreas is not able to release required insulin or needed excess quantity of insulin. 
  • Type 2 diabetes may be caused if the liver is not sensitive to insulin and mistakenly releases glucose in the blood stream even if there is enough glucose already exist in the blood.
  • Type 2 diabetes may be caused if the muscles cell are not sensitive to insulin and not properly utilizing available glucose, which in-turn rises blood glucose level.
Diabetes pancreas damage leads to Type 1 diabetes
  • Most of the cases of Type 1 diabetes are caused by autoimmune disorder. Our immune system mistakenly consider the pancreas as a foreign body and attacking it and causes damage to pancreas “islet”, which releases insulin. So no or very low secretion of insulin.
  • Type 1 diabetes may be causes by certain viruses that attacks pancreas and stops or limits its insulin production.
  • Pancreas is affected by pancreatic disease.

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